Michael J. Gough, PhD

Michael J. Gough, Ph.D. Member, Integrated Therapies Laboratory
Earle A. Chiles Research Institute
Providence Cancer Institute

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Dr. Gough is an experienced researcher of immunology. Currently, he partners with member Marka R. Crittenden M.D., Ph.D. to lead the Integrated Therapies Laboratory at the Earle A. Chiles Research Institute, a Providence Center of Excellence for immuno-oncology and cellular therapy.

Dr. Gough’s research is focused on understanding the role of immune cells in the success and failure of conventional cancer therapies, and the development of immunotherapies that target and destroy residual microscopic disease.

Along with leading the lab, Dr. Gough is also an adjunct assistant professor in the Department of Molecular Microbiology and Immunology and an adjunct clinical research assistant professor in the Department of Radiation Oncology at Oregon Health & Science University.

Integrated Therapies Lab 

The Integrated Therapies Lab is a collaborative research effort between Dr. Gough and Dr. Crittenden. It combines their expertise in surgical, medical and radiation oncology to translate hypotheses from preclinical models into more effective cancer treatments. The lab studies the ability of cytotoxic therapy to provide large-scale cancer cell death in vivo, while modifying the profile of immune cells within the tumor.

Education
  • Postdoctoral fellow, laboratory of Dr. Andrew Weinberg, Earle A. Chiles Research Institute, Providence Cancer Institute, 2004-2009 
  • Postdoctoral fellow, laboratory of Dr. Richard Vile, Mayo Clinic, 1999-2004 
  • Doctor of Philosophy in tumor immunology, The University of Leeds, 1999 
  • Master of Science in immunology, University of Birmingham, 1995 
  • Bachelor of Science in human biology and business administration, University of Aston in Birmingham, 1994 
     
Professional Experience
  • Member, Integrated Therapies Laboratory, Earle A. Chiles Research Institute, Providence Cancer Institute, 2021-present 
  • Associate member, Integrated Therapies Laboratory, Earle A. Chiles Research Institute, Providence Cancer Institute, 2017-2021 
  • Adjunct assistant professor, Department of Molecular Microbiology and Immunology, Oregon Health & Science University, 2013-present 
  • Assistant member, Integrated Therapies Laboratory, Earle A. Chiles Research Institute, Providence Cancer Institute, 2009-2017 
  • Adjunct clinical research assistant professor, Department of Radiation Oncology, Oregon Health & Science University, 2006-present 
Memberships
  • American Association for Cancer Research  
  • American Association of Immunology  
  • Chair, Institutional Animal Care and Use Committee, Providence Portland Medical Center  
  • Radiation Research Society 
  • Society for Immunotherapy of Cancer  
Awards
  • Society for Immunotherapy of Cancer Team Science Award, 2020 
  • Master of Science with distinction, Department of Immunology, University of Birmingham, 1995  
  • First class honors, human biology and business administration, University of Aston, Birmingham, 1994  

Dr. Gough’s research is published in peer-reviewed scientific and medical journals. He has partnered with colleagues on various research projects, including projects funded by the National Institutes of Health. 

View Dr. Gough’s full list of peer-reviewed publications